The Impact of Anesthetic Choice to Decrease Cancer Recurrence and Morbidity
Date
2019
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Abstract
The number of cancer patients worldwide is increasing, and surgical resection is often the first choice for removal of the primary tumor. The perioperative period is a crucial time to promote or prevent tumor recurrence by incorporating evidenced-based research into practice. There is ongoing research that inhalational anesthesia can depress the immune system, while intravenous anesthesia with propofol can inhibit tumor growth and enhance cell-mediated immunity. A thorough literature review and synthesis was completed regarding the effects of inhalational versus the intravenous anesthetic propofol in preventing cancer recurrence. The aim of this scholarly project was to increase the 2019 Advent University of Health Sciences (ADU) student registered nurse anesthetists (SRNAs) cohort’s knowledge base regarding anesthetic selection. After informed consent was obtained, a 30-minute PowerPoint presentation was conducted, and an identical pre- and post-test were given to assess for an increase in the 2019 ADU SRNAs knowledge base. A paired sample t test showed a statistically significant (p<0.0001) increase in test scores from 30.9% to 83.6%. The results of this scholarly project suggest that the 2019 ADU NAP cohort had a statistically significant increase in knowledge regarding the appropriate perioperative anesthetic selection to promote overall survival and decrease cancer relapse.
Keywords: anesthesia, anesthesia, anesthetic agents, cancer, cancer recurrence, circulating tumor cells, desflurane, immunosuppression, inhalational anesthetics, isoflurane, oncologic surgery, propofol, total intravenous anesthesia, tumor removal, and sevoflurane.
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